Wrinkle Treatment & Injectables
JULÄINE™
Collagen biostimulation for natural skin rejuvenation

At a Glance
In Brief
Collagen biostimulation with PLLA
Treatment Duration
30–45 minutes
Pain
Well tolerated, slight pricking possible
Anaesthesia
Numbing cream if needed
Downtime
Minimal, usually 1–3 days
Results
First changes after approx. 3–6 weeks
Duration of Effect
Up to 2 years
Sessions
Individual, after consultation
Price
CHF 1’200 per session
JULÄINE™ of Sweden is an injectable collagen biostimulator based on poly-L-lactic acid (PLLA), a biocompatible material that the body tolerates well and breaks down over time. The treatment stimulates the body’s own collagen production and can improve skin firmness, structure and elasticity. Because the skin forms this collagen itself, its appearance changes over several weeks and months.
Over the years, the skin loses elasticity and firmness, and fine lines, wrinkles or a tired complexion begin to show. JULÄINE™ may be considered for concerns of this kind. During the consultation, we examine the skin and talk through which areas to treat and how many sessions are appropriate.

Treatment Areas
We choose the treatment areas based on your skin’s condition and your goals.
Cheeks and Mid-Face
On the cheeks and mid-face, JULÄINE™ can improve skin firmness and elasticity. These areas can then appear more defined and lifted.
Nasolabial and Marionette Lines
Nasolabial folds run from the nose to the corners of the mouth, and marionette lines from the corners of the mouth to the chin. Treatment can soften these deeper lines and improve skin structure in the lower face.
Eye and Mouth Area
The skin around the eyes and mouth is delicate. In these areas, JULÄINE™ is used to soften fine lines and improve skin quality.
Jawline and Chin
Along the jawline and chin, treatment can strengthen skin firmness. This can help the contour look clearer and more defined.
Neck and Décolleté
The neck and décolleté often show early signs of skin ageing. Where firmness has declined, or where neck lines and crêpe-like lines have formed, JULÄINE™ can help the skin look smoother and firmer.
Backs of the Hands
JULÄINE™ can also improve skin quality and firmness on the backs of the hands, leaving the skin looking smoother and well cared for.
How does JULÄINE™ work?
JULÄINE™ is based on LASYNPRO™ technology, which uses highly purified microspheres of poly-L-lactic acid, tiny particles of PLLA. They are placed precisely in the deeper layers of the skin, where they trigger a controlled biological response.
Here, PLLA acts as a stimulus for fibroblasts, the cells that produce important components of connective tissue. Over the following weeks, new collagen forms, particularly types I and III, together with elastin. This new collagen strengthens the extracellular matrix, the supporting framework of connective tissue, and can soften wrinkles and skin laxity.
The body slowly breaks down the microspheres, while the newly formed collagen remains. For this reason, the changes build up over time and can last for a long period. JULÄINE™ can be combined with selected aesthetic treatments, planned on a case-by-case basis.
- PLLA microspheres with LASYNPRO™ technology
- Stimulus for the skin’s fibroblasts
- New type I and III collagen and elastin
- Biocompatible and biodegradable
- Develops over weeks and months

Why JULÄINE™ at Aesthetics Medical?
Experience with Biostimulators
Our FMH specialist, Dr. med. (I) Ranieri Mazzei, has many years of experience with biostimulators and aesthetic injections. Treatment is tailored to your skin condition, anatomy and goals.
Precise Placement
JULÄINE™ is injected precisely into the intended skin layers. Careful technique and placement are essential for even stimulation and a natural-looking effect.
Planning Based on Your Skin
Before the first session, we assess skin quality, firmness and volume. The number of treatments and the intervals between them are based on this assessment.
Your Own Features
We aim for a visible improvement in skin quality and firmness while keeping your natural facial features. The change develops over time and stays in harmony with your face.
A Long-Term Approach
JULÄINE™ is designed to improve skin structure progressively. We therefore see the treatment as part of a longer-term concept for the condition of your skin.

What does the treatment involve?
Consultation
We analyse your skin and discuss what you would like to achieve. We then agree on the areas to be treated and your treatment plan.
Preparation
The skin is cleansed and disinfected. A numbing cream can be applied beforehand if needed.
Injection
JULÄINE™ is injected into the skin with a fine needle, and the amount and distribution are adjusted to your skin. A session usually takes 30–45 minutes.
Aftercare
After the injection, we check the skin and soothe it if necessary. You receive recommendations for the first few days and know whom to contact with any questions.
The Following Months
The effect develops over several weeks and months, and the skin can look increasingly firm, smooth and refined. If further sessions are planned, they follow at the agreed interval.
| JULÄINE™, two sessions | CHF 2'400 |
| JULÄINE™, one session | CHF 1'200 |
You will find out the exact cost after the initial consultation.
Frequently Asked Questions
How does the treatment work and how long does it take?
After the consultation, the skin is cleansed, disinfected and, if needed, prepared with anaesthetic cream. We then inject JULÄINE™ with a fine needle into the areas agreed beforehand. A session generally takes 30–45 minutes.
Is the treatment painful, and is anaesthesia used?
Thanks to the fine injection technique, the treatment is generally well tolerated. A mild feeling of tension or a pricking sensation may occur during the injection. If you wish, we apply a numbing cream beforehand.
What risks and side effects are possible?
As with any injectable treatment, mild redness, swelling, small bruises or tenderness may occur temporarily. These reactions are mild and settle on their own; small nodules form rarely and usually recede as well. Serious complications are very rare. Before treatment, we discuss with you which risks are relevant in your case and whether the treatment is suitable for you.
What should I consider before the treatment?
First, we assess your skin and discuss your goals in an initial consultation. You receive clear preparation instructions before your appointment, including advice on medication and sun exposure. We clarify during the consultation what applies in your case.
What should I consider after the treatment?
For the first 24–48 hours, avoid intense physical activity, heat such as saunas or sunbeds, and strong sun exposure. Please also avoid rubbing or massaging the treated areas firmly. Use SPF 50+ sun protection consistently and avoid smoking if possible, as it impairs collagen production. You will receive all recommendations after the treatment.
How long does recovery take after the treatment?
Downtime after a JULÄINE™ treatment is minimal. Mild redness or swelling can last 1–3 days and can be covered well with make-up from the following day. Most people can return to work immediately or after 1–2 days.
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When do results become visible?
The first improvements in skin quality may appear after around 3–6 weeks, once the regeneration process begins. The full effect develops over around 3–6 months as the skin continues to build collagen.
How long do the results last?
The effect can remain visible for up to 2 years. The body breaks down the newly formed collagen only slowly. Maintenance treatments can extend the effect, and your doctor will advise you on when one makes sense.
How many sessions are usually needed?
The number of sessions is determined individually. It depends on the condition of your skin, your age and what you would like to achieve. We agree on the treatment plan and the intervals between sessions together during the consultation.
Who is the treatment suitable for?
JULÄINE™ can be used on most skin types. It is mainly considered when the skin has lost firmness, elasticity and structure, or when fine lines and wrinkles have appeared. We clarify in a personal consultation whether it is right for you.
How much does the treatment cost?
One JULÄINE™ treatment costs CHF 1’200, two treatments cost CHF 2’400. Aesthetic treatments are usually paid for privately. We will confirm the exact amount for your treatment plan after the consultation.
Personal Consultation
Start now.
Every treatment starts with a conversation and a 3D analysis.